Just a quick update on my experience to date with the ScanScience kit. I’ve now tried scanning negative film (35mm Kodak Ektar 100), and the benefits are much clearer, although mainly due to the fluid mount keeping the film flat.
Here, the top scan is using the standard filmstrip holder, and the bottom one is using a fluid mount. These 100% screen shots are from the edge of the film: the scans were manually focussed at the centre of the strip, and there the difference is minimal.
The colour differences are not significant - I didn’t take much notice of this during the scan, and just let Silverfast do its thing. You can’t see it here, but the fluid mount scan has slightly more detail and micro contrast. Nothing overwhelming though.
So the conclusion is in this case that it is well worth the trouble - but the advantages over a carefully prepared dry glass holder, for 35mm film, remain small.